Amir Ardeshir, DVM, PhD
Associate Professor of Microbiology and Immunology
Education & Affiliations
Research
Dr. Ardeshir's lab focuses on deciphering the complex interplay between the microbiome and host immune systems to enhance health and well-being. Employing rhesus macaque models and a systems biology methodology, the lab investigates microbiome dynamics and immune system development to uncover the mechanisms underlying host-microbiome interactions. This knowledge is harnessed to design practical interventions for preventing or treating infectious diseases.
Dr. Ardeshir is also the Unit Leader for the Durable Medicine Model Unit, a unique research hub supported by the Gates Foundation that accelerates the development of durable protein therapeutics targeting HIV, malaria, and tuberculosis to deliver affordable, scalable solutions for high-burden populations in low- and middle-income countries.
View Dr. Ardeshir's publications on PubMed here
Research programs
- Unraveling the mechanisms that govern the establishment and maintenance of gut microbiota throughout life.
- Examining the role of gut microbiota in shaping the development and function of the immune system, including responses to vaccines and interventions against infectious diseases.
- Evaluating the consequences of disruptions in the balanced gut flora and their long-term impact on health and disease.
- Creating effective therapeutic strategies to modulate microbial communities and optimize host-microbiota interactions for improved health outcomes.
- Employing viral entry inhibitor antibody-like molecules for disease prevention and treatment.
